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一、项目编号:07
二、项目名称:年产6000吨基因工程酶法合成D-对羟基苯甘氨酸邓钾盐
三、项目行业:医药化工
四、项目背景和建设条件:D(-)对羟基苯甘氨酸邓钾盐是一种高新技术药物原材料。它是β-内酰胺类半合成抗生素的重要侧链,主要用于合成羟氨苄青霉素和羟氨苄头孢菌素等医药产品。羟氨苄青霉素和克拉维酸合成的奥格门汀预测是未来10年世界最畅销的六种抗生素之一。
五、项目准备进展情况:项目申报阶段。
六、建设项目及建设内容:公司计划建成年产6000吨基因工程酶法合成D-对羟基苯甘氨酸邓钾盐。新建生产车间和配套设施。
七、财务评价:投资总额:9929万元;引资额:500万美元;投资回收期:5.23年(含建设期)。
八、合作内容:外方主要以资金投入,中方提供工艺技术、生产场地、人员、能源等投入。
九、中方项目单位情况:浙江普洛医药科技有限公司是一家集研究、开发、生产经营医药、化工产品于一体的大型企业。公司拥有总资产人民币3亿多元,员工1200余人,其中科研和技术管理人员占职工总数的46%以上。公司为国家火炬计划重点高新技术企业、浙江省资源综合利用企业,已通过ISO9001:2000国际质量保证体系认证和ISO14001:1996环境管理体系认证。公司拥有自营进出口权。
十、项目方可提供的条件:普洛公司自筹5329万元,约合666万美元,提供土地、厂房、电力、水源等基础设施。
十一、联系方法:
联系人姓名:陈 庆 职 务:总经理助理
联系电话:0579-86558315 传 真:0579-86557819
邮政编码:322118 通讯地址:浙江省东阳市横店工业区
电子邮箱:lyqlu@tom.com
Cooperative Investing Projects in City of Dongyang
Ⅰ. Project No.:07
Ⅱ. Project Name: D-p-Hydroxyphenylglycine Dipotassium Salt, synthesized by genetic engineering enzyme method, with annual output of 6000 tons.
Ⅲ. Industry to Which the Project Belongs: Pharmaceutical & Chemical Industry
Ⅳ. Project background and construction conditions
D(-)-p-Hydroxyphenylglycine Diphtassium Salt is a new- and high-tech raw medicinal material. It is the significant side chain of β-lactam semi-synthetic antibiotics, and is mainly used in synthesis of pharmaceutical products such as Amoxicillin and Cephaloglycin, etc. It is expected that, Augmentin, combined with Amoxicillin and Clavulanate, is one of the most salable antibiotics in the 10 coming years.
Ⅴ. Project Progression: Stage of project application
Ⅵ. Construction Scale and Construction Content:
The company plans to establish a product line for synthesis of D-p-Hydroxyphenylglycine Dipotassium Salt by genetic engineering enzyme method, with an annual output of 6000 tons, and to establish production workshops and supporting facilities.
Ⅶ. Financial Assessment: Total investment: RMB 99.29 million yuan
Investment Attracted: US $5 million Recovery Period of Investment: 5.23 year (including construction period)
Ⅷ. Cooperation content:
The foreign party mainly provides fund, and the Chinese party mainly provides process techniques, production site, personnel, and energy, etc.
Ⅸ. Condition of the Chinese Party in the Project:
Zhejiang Puluo Pharmaceutical Sci-tech Co., Ltd., is a large-scale enterprise, integrated research, development, as well as production and operation of pharmaceutical and chemical products. It has total assets of more than RMB 0.3 billion yuan, and more than 1200 employees, including more than 46% of scientific researchers and managers among them. It is a key new- and high-tech enterprise of the National Torch Plan, and an enterprise for comprehensive utilization of resources of Zhejiang Province. It has passed verification of ISO9001:2000, International Quality Assurance System, and of ISO14001:1996, Environmental Management System. It has the self-managed import-export right.
Ⅹ. Available Conditions by the Project Party:
Puluo Company raises itself RMB 53.29 million yuan, approximately US $ 6.66 million, and provide infrastructure such as land, factory building, electric power, and water source, etc.
Ⅺ. Contact Information:
Name: Chen Qing Post: Director of project department
Tel: 0579-86558315 Fax: 0579-86557819
Zip code: 322118
Address: Hengdian Industrial Park, Dongyang City, Zhejiang Province
Email: lyqlu@126.com
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